Smad4 as a Transcription Corepressor for Estrogen Receptor α
نویسندگان
چکیده
منابع مشابه
LSD1 engages a corepressor complex for the activation of the estrogen receptor α by estrogen and cAMP
The estrogen receptor α (ERα) is a transcription factor that can be directly activated by estrogen or indirectly by other signaling pathways. We previously reported that activation of the unliganded ERα by cAMP is mediated by phosphorylation of the transcriptional coactivator CARM1 by protein kinase A (PKA), allowing CARM1 to bind ERα directly. This being insufficient by itself to activate ERα,...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2003
ISSN: 0021-9258
DOI: 10.1074/jbc.m212332200